Translation Optimization Services for Biomanufacturing
We help biomanufacturers solve difficult protein expression challenges through expert-guided analysis of translation efficiency and RNA regulation.
A Collaborative Approach
Our services are offered as tailored collaborations designed around your expression system and specific production challenges. We analyze tRNA pools and RNA modifications to generate actionable insights for optimizing your process.
Our Offer
We help you optimize protein expression by uncovering what truly limits translation. By analyzing key determinants such as tRNA availability and RNA modifications, we identify hidden bottlenecks in your system and enable targeted improvements in yield and process robustness:
- Quantitative tRNA profiling to evaluate codon–tRNA matching and translation efficiency
- RNA modification analysis to reveal regulatory effects on translation
- Identification of bottlenecks driving low yield or unstable production
Expression Systems
Our approach is agnostic with regard to the expression system used and can be flexibly applied to a variety of production organisms, such as Escherichia coli, Pichia pastoris, algae, etc.